Comparative Genomics of Non-Model Invertebrates

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IGNITE research presents tool for pattern detection in chromosome contact maps

A research article recently published in the Nature Communications journal presents an algorithm inspired from computer vision that can detect patterns in contact maps. The paper called "Computer vision for pattern detection in chromosome contact maps" outlines the development of the Chromosight algorithm which provides insights into genomes by using visible patterns on genome-wide contact maps generated by chromosome conformation captu... show more

Exploring the grape phylloxera and its genome sequence: an IGNITE-funded study

An IGNITE-supported paper investigating the invasion of the aphid-like grape phylloxera Daktulosphaira vitifoliae is now available in the BMC Biology Journal.  Biological invasions are known to viciously affect ecosystems, as well as human species and economies, by threatening food production. According to the study, the grape phylloxera Daktulosphaira vitifoliae is one of the few biological pests which affects cultivated plant species to... show more

IGNITE research presents a new tool for chromosome-level genome scaffolding

A research article recently published in the Genome Biology journal presents a new software for genome scaffolding on a chromosome level. The paper called "InstaGRAAL: chromosome-level quality scaffolding of genomes using a proximity ligation-based scaffolder" outlines the development and testing of the InstaGRAAL software for large genome assembly based on chromosomal conformation capture data. A step-by-step top to bottom corre... show more

IGNITE researchers study the errors in orthology inference and their effects on evolutionary analyses

IGNITE researchers, Paschalis Natsidis (ESR 12) and Prof. Max Telford, have recently conducted a study on the Systematic errors in inference and their effects on evolutionary analyses, made available in the iScience Journal. The publication has its main focus on investigating the errors in identifying orthologous genes and has found that they increase with higher rates of evolution. Orthology is a type of homology where the homologous genes or... show more

IGNITE research calls for extreme caution towards results of SARS-CoV-2 phylogenetic analysis

A research article recently published in the journal Molecular Biology and Evolution provides an investigation into phylogenetic methods used to investigate the evolution and spread of COVID-19. The paper called "Phylogenetic Analysis of SARS-CoV-2 Data Is Difficult" analyses SARS-CoV-2 evolution using a data-driven approach and provides a review of the difficulties of inferring reliable phylogenies of the SARS-CoV-2 virus.   ... show more